Abstract—The aim of this study was to develop a process of extraction oxyresveratrol from Artocarpus lakoocha heartwood using a maceration method. The influences of types of solvent, a concentration of solvent, and time to extract on the yield of oxyresveratrol were studied. In addition, the antioxidant capacity of the extract was investigated. The quantitation of oxyresveratrol was measured by high-performance liquid chromatography (HPLC) analysis, and antioxidant activity was analyzed by 1,1’-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay. The results indicated that 70-percent ethanol solvent by volume for 6 hours could extract the optimum oxyresveratrol at 13.09 percent of the dry weight of Artocarpus lakoocha, and antioxidant efficiency had an IC₅₀ of 47.70 μg/ml.

Index Terms—Antioxidants, Artocarpus lakoocha roxb., extraction, oxyresveratrol.

Kittiya Jiratanakittiwat1, Chutimon Satirapipathkul is with Chemical Engineering Research Unit for Value Adding of Bioresources, Department of Chemical Engineering, Chulalongkorn University, Bangkok, Thailand (email: Chutimon.S@chula.ac.th).
Dusadee Charnvanich is with Department of Pharmaceutics and Industrial Pharmacy, Chulalongkorn University, Bangkok, Thailand.

Cite: Kittiya Jiratanakittiwat, Chutimon Satirapipathkul, Dusadee Charnvanich, "The Influences of Extraction on the Quantity of Oxyresveratrol from Artocarpus lakoocha Roxb.," International Journal of Bioscience, Biochemistry and Bioinformatics vol. 10, no. 2, pp. 110-116, 2020.

Copyright © 2020 by the authors. This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).