Abstract—Bronchial carcinoma is the world’s most common type of cancer associated with the mutations of ras, src, and myc genes and tumor suppressor proteins p53 and BRCA1 along with the epidermal growth factor receptors (EGFR). 3D structures of these proteins were generated using homology modeling. Active compounds of the medicinal herbs and plants were selected on the basis of their properties. Chemical structures of the active components of these herbs were drawn using chemsketch, combined and converted to*.pdb. The four proteins were successfully docked with the combination of active components.

Index Terms—Bronchial carcinoma, mutation, homology modeling, ayurveda, docking, drug designing.

Preenon Bagchi, Research Scholar, Dept. of Bioinformatics,SRM University, Kattankulathur, Tamil Nadu, India (e-mail: prithish.bagchi@gmail.com)
Nikita Sinha, Student, Department of Computer Science, Jamia Millia Islamia University, New Delhi, India.
Ajit Kar, Chief Chemist, Satsang Herbal Research Laboratory, S R Mandir, Satsang, Deoghar, Jharkhand, India.
Mahesh. M, CEO,Azyme Bioscience Pvt. Ltd, 9th Block, Jayanagar, Bangalore, Karnataka, India.


Cite: Preenon Bagchi, Nikita Sinha, Ajit Kar, and Mahesh. M, "Ayur-Informatics: Establishing an Ayurvedic Remedy for Bronchial Carcinoma," International Journal of Bioscience, Biochemistry and Bioinformatics vol. 1, no. 1, pp. 41-46, 2011.