Abstract—Micro-RNAs are small non-coding RNAs having important biological functions such as gene regulation and disease causality. Network analysis on miRNA-related network can help understanding gene regulation mechanism and propose cures for miRNAs related diseases. In this paper, we integrated miRNA-related data from three state of the art databases, miRTarBase, miRBase and HMDD v2.0 to construct a human miRNAs, gene targets and diseases network. We then performed network statistics analysis, disease cluster analysis and gene-disease association analysis on the network. The results show that there exists community structures in the network, similar disease are associated with similar miRNAs with enriched biological functions and gene-disease pairs connected by multiple paths in the network are more likely to have biological association.