Abstract—In this study we performed comprehensive biological and morphological analysis of dermis-derived stem cells and compared them with bone marrow- and adipose tissue-derived stem cells. According to obtained results we can emphasize that analyzed somatic stem cells shared morphological features, expression of surface antigens as well as growth kinetics, but differ in chondrogenic potential. Skin-derived stem cells have an inferior potential for chondrogenic differentiation. So this fact decreases their potential for cartilage tissue engineering.

Index Terms—Biological characteristics, chondrogenic differentiation, morphology, somatic stem cells.

M. Bohac, and J. Fedeles are with the Department of Plastic, Reconstructive and Aesthetic Surgery, Faculty of Medicine, Comenius University, Pažítkova 4, 82101 Bratislava, Slovakia (e-mail: bohac.md@gmail.com).
S. Polak, and J. Rusnakova are with the Institute of Histology and Embryology, Faculty of Medicine, Comenius University, Sasinkova 4, 81108 Bratislava, Slovakia (e-mail: stefan.polak@fmed.uniba.sk).
Z. Varchulova Novakova and L. Danisovic are with the Institute of Medical Biology, Genetics and Clinical Genetics, Faculty of Medicine, Comenius University, Sasinkova 4, 81108 Bratislava, Slovakia (e-mail: lubos.danisovic@fmed.uniba.sk).

 

Cite:M. Bohac, S. Polak, J. Fedels, Z. Varchulova Novakova, J. Rusnakova, and L. Danisovic, "Do Dermis-Derived Stem Cells Have the Same Characteristics as Bone Marrow- and Adipose Tissue-Derived Stem Cells?," International Journal of Bioscience, Biochemistry and Bioinformatics vol. 3, no. 6, pp. 630-634, 2013.