Abstract—This study evaluated the effect of combining autogenous bone with synthetic bioactive glass – hydroxyapatite in the treatment of vertical periodontal defects. Ten subjects with chronic periodontitis were treated in a split mouth design with either a combination of bioactive glass – hydroxyapatite and autogenous bone or bioactive glass– hydroxyapatite alone. Clinical and radiographic parameters showed significant improvement within groups in the soft and hard tissue parameters assessed at six months. However, there was no statistically significant difference between the groups. Only marginal benefits were observed on addition of autogenous bone to the synthetic graft.

Index Terms—Autogenous cortical bone particulate, bioactive glass, periodontal defects, chronic periodontitis.

Pratibha P. K. is with the Manipal College of Dental Sciences, Manipal University, India (Tel.: 09448724121; fax: 0820 – 2571 966 ; e-mail: bg_pratibha@ yahoo.co.in).
A. Bhide was with Manipal College of Dental Sciences, Manipal University, India (e-mail: dr_amey_bhide@yahoo.com).
G. S. Bhat is with the Department of Periodontics at Manipal College of Dental Sciences, Manipal University, India (e-mail: subraya68@yahoo.com).

Cite: A. Bhide, Pratibha P. K., and G. S. Bhat, "Evaluation of Autogenous Cortical Bone Particulate with Bioactive Glass-Synthetic Hydroxyapatite in Treatment of Periodontal Bone Defects," International Journal of Bioscience, Biochemistry and Bioinformatics vol. 2, no. 1, pp. 36-39, 2012.